(19)

(11)

EP 1 265 607 A2

(12)

(88) Date of publication A3: 25.04.2002 (43) Date of publication: 18.12.2002 Bulletin 2002/51 (21) Application number: 01956186.9 (22) Date of filing: 16.01.2001

(51) International Patent Classification (IPC)7: A61K 31/40 (86) International application number: PCT/US0100/007 (87) International publication number: WO 0106/6110 (13.09.2001 Gazette 2001/37)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 09.03.2000 US 188039 P (71) Applicant: ELI LILLY AND COMPANY Indianapolis, Indiana 46285 (US)	(72) Inventors: MACIAS, William, Louis Indianapolis, IN 46234 (US) MEADOR, Vincent, Phillip Greenfield, IN 46140 (US) (74) Representative: Burnside, Ivan John  Eli Lilly and Company LimitedEuropean Patent OperationsErl Wood ManorSunninghill Road Windlesham, Surrey GU20 6PH Windlesham, Surrey GU20 6PH (GB)