(19)

(11)

EP 1 267 837 A1

(12)

(43) Date of publication: 02.01.2003 Bulletin 2003/01 (21) Application number: 01920538.4 (22) Date of filing: 20.03.2001

(51) International Patent Classification (IPC)7: A61K 9/14, A61K 33/42, A61K 33/00, A01N 59/26, A01N 59/24, C08K 3/28 (86) International application number: PCT/US0108/806 (87) International publication number: WO 0107/0199 (27.09.2001 Gazette 2001/39)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 20.03.2000 US 190546 P 20.03.2000 US 190571 P (71) Applicant: Novovascular, Inc. Baltimore, MD 21201 (US)	(72) Inventors: ZHAO, Yi-Ju Ellicot City, MD 21042 (US) BRAATZ, James, A. Beltsville, MD 20705 (US) ROSEN, Gerald, M. Lutherville, MD 21093 (US) (74) Representative: Desaix, Anne et al Ernest Gutmann - Yves Plasseraud S.A.3, rue Chauveau-Lagarde 75008 Paris 75008 Paris (FR)