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EP 1 267 864 A1

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(43) Date of publication: 02.01.2003 Bulletin 2003/01 (21) Application number: 00940733.9 (22) Date of filing: 31.03.2000

(51) International Patent Classification (IPC)7: A61K 31/335, A61K 47/44, A61K 9/48, A61K 9/02 (86) International application number: PCT/IN0000/039 (87) International publication number: WO 0107/4353 (11.10.2001 Gazette 2001/41)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (71) Applicant: COUNCIL OF SCIENTIFIC &INDUSTRIAL RESEARCH New Delhi 110001 (IN)

(72) Inventors: DUTTA, Guru Prakash,Central Institute Lucknow 226 015,Uttar Pradesh (IN) JAIN, Dharm Chand,Central Institute Lucknow 226 015,Uttar Pradesh (IN) BHAKUNI, Rajendra Singh,Central Institute Lucknow 226 015,Uttar Pradesh (IN) SAXENA, Sudhanshu,Central Institute Lucknow 226 015,Uttar Pradesh (IN) DHAWAN, Sangeeta,Central Institute Lucknow 226 015,Uttar Pradesh (IN) KHANUJA, Suman Preeet Singh,Central Institute Lucknow 226 015,Uttar Pradesh (IN) KUMAR, Sushil,Central Institute Lucknow 226 015,Uttar Pradesh (IN) TRIPATHI, Renu,Central Drug Research Institute Lucknow 226 015,Uttar Pradesh (IN) UMESH, Aseem,Central Drug Research Institute Lucknow 226 001,Uttar Pradesh (IN) KAMAL, Nuzhat,Central Drug Research Institute Lucknow 226 001,Uttar Pradesh (IN) DWIVEDI, Anil Kumar,Central Drug Research Inst. Lucknow 26 001,Uttar Pradesh (IN) SINGH, Satyawan,Central Drug Research Institute Lucknow 226 001,Uttar Pradesh (IN) (74) Representative: Schwarz, Albin, Dr. et al PatentanwaltWipplingerstrasse 32/22 1010 Wien 1010 Wien (AT)