(19)
(11) EP 1 267 898 A2

(12)

(88) Date of publication A3:
14.02.2002

(43) Date of publication:
02.01.2003 Bulletin 2003/01

(21) Application number: 01926709.5

(22) Date of filing: 06.04.2001
(51) International Patent Classification (IPC)7A61K 35/50, A61K 39/40, A61K 39/42, A61K 39/44, A61K 39/395
(86) International application number:
PCT/US0111/327
(87) International publication number:
WO 0107/6531 (18.10.2001 Gazette 2001/42)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 07.04.2000 US 195854 P
21.02.2001 US 269906 P

(71) Applicant: University of Maryland, Baltimore
Baltimore,Maryland 21201 (US)

(72) Inventors:
  • POLLI, James, E.
    Ellicott City, MD 21403 (US)
  • COOP, Andrew
    Baltimore, MD 21244 (US)
  • MAEDA, Dean, Y.
    Bothell, WA 98012 (US)
  • LENTZ, Kimberley, A.
    Durham, CT 06422 (US)

(74) Representative: Jones, Elizabeth Louise 
Frank B. Dehn & Co.,179 Queen Victoria Street
London EC4V 4EL
London EC4V 4EL (GB)

   


(54) BILE ACID CONTAINING PRODRUGS WITH ENHANCED BIOAVAILABILITY