(19)

(11)

EP 1 267 906 A1

(12)

(43) Date of publication: 02.01.2003 Bulletin 2003/01 (21) Application number: 01922708.1 (22) Date of filing: 27.03.2001

(51) International Patent Classification (IPC)7: A61K 38/00, A61P 25/28, C07K 5/06 (86) International application number: PCT/US0109/703 (87) International publication number: WO 0107/2324 (04.10.2001 Gazette 2001/40)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: LT LV RO SI (30) Priority: 28.03.2000 US 192517 P (71) Applicant: Bristol-Myers Squibb Pharma Company Princeton,New Jersey 08443-4000 (US)	(72) Inventor: THOMPSON, Lorin, Andrew Wilmington, DE 19809 (US) (74) Representative: Beacham, Annabel Rose  Frank B. Dehn & Co.,European Patent Attorneys,179 Queen Victoria Street London EC4V 4EL London EC4V 4EL (GB)