(19)

(11)

EP 1 267 936 A2

(12)

(88) Date of publication A3: 02.05.2002 (43) Date of publication: 02.01.2003 Bulletin 2003/01 (21) Application number: 01914662.0 (22) Date of filing: 02.03.2001

(51) International Patent Classification (IPC)7: A61K 47/48, A61K 31/4745 (86) International application number: PCT/US0106/829 (87) International publication number: WO 0107/4401 (11.10.2001 Gazette 2001/41)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 31.03.2000 US 539982 (71) Applicant: SuperGen, Inc. Dublin, CA 94568 (US)	(72) Inventors: RUBINFELD, Joseph Danville, CA 94506 (US) WRENN, Simeon, M. Danville, CA 94526 (US) (74) Representative: Gallagher, Kirk James et al D Young & Co,21 New Fetter Lane London EC4A 1DA London EC4A 1DA (GB)