(19)
(11) EP 1 268 782 A2

(12)

(88) Date of publication A3:
28.02.2002

(43) Date of publication:
02.01.2003 Bulletin 2003/01

(21) Application number: 01918561.0

(22) Date of filing: 13.03.2001
(51) International Patent Classification (IPC)7C12N 15/12, C12N 15/62, C12N 15/86, C07K 14/775, C07K 16/18, C12N 5/10, C12N 5/12, A61K 38/17, G01N 33/577, G01N 33/68
(86) International application number:
PCT/US0107/826
(87) International publication number:
WO 0106/8852 (20.09.2001 Gazette 2001/38)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 13.03.2000 US 189008 P

(71) Applicant: Amgen Inc.
Thousand Oaks, CA 91320-1799 (US)

(72) Inventors:
  • EDWARDS, Carl, K., III
    Thousand Oaks, CA 91362 (US)
  • BURGER, Danielle
    CH-1227 Carouge (CH)
  • DAYER, Jean-Michel
    CH-1208 Geneva (CH)
  • KOHNO, Tadahiko
    Thousand Oaks, CA 91362 (US)

(74) Representative: Richardson, Kate et al
Forrester & Boehmert,Pettenkoferstrasse 20-22
80336 München
80336 München (DE)

   


(54) APOLIPOPROTEIN-A-I REGULATION OF T-CELL SIGNALLING