(19)
(11) EP 1 268 820 A2

(12)

(88) Date of publication A3:
25.04.2002

(43) Date of publication:
02.01.2003 Bulletin 2003/01

(21) Application number: 01922383.3

(22) Date of filing: 12.03.2001
(51) International Patent Classification (IPC)7: C12N 15/61, C12N 9/90, C12N 5/10, C07K 16/40, C12Q 1/68, G01N 33/50
(86) International application number:
PCT/US0108/147
(87) International publication number:
WO 0106/8880 (20.09.2001 Gazette 2001/38)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 10.03.2000 US 188306 P
09.03.2001 US 802373

(71) Applicant: SCHERING AKTIENGESELLSCHAFT
13342 Berlin (DE)

(72) Inventors:
  • BROOKS, Alan, R.
    Clayton, CA 94517 (US)
  • DENG, Gary, G.
    Benicia, CA 94510 (US)
  • RUBANYI, Gabor, M.
    Alamo, CA 94507 (US)

(74) Representative: Murphy, Colm Damien et al
Boult Wade Tennant,Verulam Gardens,70 Gray's Inn Road
London WC1X 8BT
London WC1X 8BT (GB)

   


(54) ESTROGEN-REGULATED MYO-INOSITOL PHOSPHATE SYNTHASE: COMPOSITIONS AND METHODS OF USE