(19)

(11)

EP 1 269 193 A2

(12)

(88) Date of publication A3: 10.05.2002 (43) Date of publication: 02.01.2003 Bulletin 2003/01 (21) Application number: 01920239.9 (22) Date of filing: 08.03.2001

(51) International Patent Classification (IPC)7: G01N 33/574, G01N 33/58, G01N 33/577, G01N 33/543, G01N 33/573, C12Q 1/37 (86) International application number: PCT/US0107/393 (87) International publication number: WO 0106/9260 (20.09.2001 Gazette 2001/38)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 13.03.2000 US 188861 P (71) Applicant: Research Foundation forMental Hygiene, Inc. Albany, NY 12229 (US)	(72) Inventors: PULLARKAT, Raju, K. Staten Island, NY 10314 (US) JUNAID, Mohammad, A. Dayton, NJ 08810 (US) (74) Representative: Jump, Timothy John Simon  Venner Shipley & Co.20 Little Britain London EC1A 7DH London EC1A 7DH (GB)