(19)

(11)

EP 1 272 508 A2

(12)

(88) Date of publication A3: 10.05.2001 (43) Date of publication: 08.01.2003 Bulletin 2003/02 (21) Application number: 00966802.1 (22) Date of filing: 21.09.2000

(51) International Patent Classification (IPC)7: C07K 1/14, C07K 14/81, C12N 15/82 (86) International application number: PCT/US0026/005 (87) International publication number: WO 0102/1270 (29.03.2001 Gazette 2001/13)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 21.09.1999 US 154923 P (71) Applicant: Prodigene Inc. College Station, TX 77845 (US)	(72) Inventor: NIKOLOV, Zivko College Station, TX 77845 (US) (74) Representative: Duffy, Assumpta Dympna et al F. R. Kelly & Co.,27 Clyde Road,Ballsbridge Dublin 4 Dublin 4 (IE)