(19)

(11)

EP 1 274 422 A1

(12)

(43) Date of publication: 15.01.2003 Bulletin 2003/03 (21) Application number: 00921658.1 (22) Date of filing: 04.04.2000

(51) International Patent Classification (IPC)7: A61K 31/366, A61P 35/00, A61P 35/02, A61P 43/00 (86) International application number: PCT/US0008/904 (87) International publication number: WO 0107/4355 (11.10.2001 Gazette 2001/41)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (71) Applicant: Novartis AG 4056 Basel (CH)	(72) Inventors: LASSOTA, Peter Succasunna, NJ 07876 (US) JAGOE, Christopher, T. Chatham, NY 07928 (US) (74) Representative: Gros, Florent et al Novartis AG 4002 Basel 4002 Basel (CH)