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EP 1 276 713 A1

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(43) Date of publication: 22.01.2003 Bulletin 2003/04 (21) Application number: 01924359.1 (22) Date of filing: 27.03.2001

(51) International Patent Classification (IPC)7: C07C 261/00, A61K 38/00 (86) International application number: PCT/US0109/756 (87) International publication number: WO 0107/2699 (04.10.2001 Gazette 2001/40)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 27.03.2000 US 192260 P (71) Applicant: The Scripps Research Institute La Jolla, CA 92037 (US)	(72) Inventors: BOGER, Dale, L. La Jolla, CA 92037 (US) CHERESH, David, A. Encinitas, CA 92024 (US) (74) Representative: Vossius, Volker, Dr. et al Patent- und RechtsanwaltskanzleiGeibelstrasse 6 81679 München 81679 München (DE)