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(11)

EP 1 276 737 A1

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(43) Date of publication: 22.01.2003 Bulletin 2003/04 (21) Application number: 01908037.3 (22) Date of filing: 28.02.2001

(51) International Patent Classification (IPC)7: C07D 401/04, A61K 31/415 (86) International application number: PCT/IB0100/277 (87) International publication number: WO 0108/3470 (08.11.2001 Gazette 2001/45)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 28.04.2000 US 200432 P (71) Applicant: Pfizer Products Inc. Groton,Connecticut 06340 (US)	(72) Inventors: CHEN, Weichao George,Pfizer Global R & D Groton, CT 06340 (US) COX, Eric David,Pfizer Global R & D Groton, CT 06340 (US) GUZMAN-PEREZ, Angel,Pfizer Global R& D Groton, CT 06340 (US) (74) Representative: Sewell, Richard Charles  UK Patent Department,Pfizer Limited,Ramsgate Road Sandwich,Kent CT13 9NJ Sandwich,Kent CT13 9NJ (GB)