(19)

(11)

EP 1 278 553 A2

(12)

(88) Date of publication A3: 02.05.2002 (43) Date of publication: 29.01.2003 Bulletin 2003/05 (21) Application number: 01933128.9 (22) Date of filing: 04.05.2001

(51) International Patent Classification (IPC)7: A61K 49/08 (86) International application number: PCT/US0114/665 (87) International publication number: WO 0108/2795 (08.11.2001 Gazette 2001/45)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 04.05.2000 US 202108 P 04.05.2000 US 201817 P 05.05.2000 US 203224 P 16.11.2000 US 716175 17.11.2000 US 716178 (71) Applicant: Research Corporation Technologies, Inc Tucson,Arizona 84711-3365 (US)	(72) Inventor: MEADE, Thomas, J. Altadena, CA 91001 (US) (74) Representative: Kiddle, Simon John et al Mewburn Ellis,York House,23 Kingsway London WC2B 6HP London WC2B 6HP (GB)