(19)

(11)

EP 1 278 753 A2

(12)

(88) Date of publication A3: 16.08.2001 (43) Date of publication: 29.01.2003 Bulletin 2003/05 (21) Application number: 00944098.3 (22) Date of filing: 07.07.2000

(51) International Patent Classification (IPC)7: C07D 493/20, A61K 31/357, A61P 33/06 // (C07D493/20, 323:00, 321:00), C07D311:00 (86) International application number: PCT/GB0002/518 (87) International publication number: WO 0100/4123 (18.01.2001 Gazette 2001/03)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 09.07.1999 GB 9916012 (71) Applicant: UFC LIMITED Manchester M15 6SY (GB)	(72) Inventors: O'NEILL, Paul Michael Wavertree,Liverpool L15 7JE (GB) WARD, Stephen Andrew Croxeth Park,Liverpool L12 0BS (GB) (74) Representative: Wilson Gunn M'Caw  41-51 Royal Exchange,Cross Street Manchester M2 7BD Manchester M2 7BD (GB)