(19)

(11)

EP 1 278 769 A2

(12)

(88) Date of publication A3: 11.07.2002 (43) Date of publication: 29.01.2003 Bulletin 2003/05 (21) Application number: 01923542.3 (22) Date of filing: 19.04.2001

(51) International Patent Classification (IPC)7: C07K 14/35, A61K 38/00, C12N 1/12 (86) International application number: PCT/DK0100/276 (87) International publication number: WO 0107/9274 (25.10.2001 Gazette 2001/43)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 19.04.2000 DK 200000666 21.02.2001 DK 200100283 (71) Applicant: Statens Serum Institut 2300 Copenhagen S (DK)	(72) Inventors: AGGER, Else, Marie DK-2300 Copenhagen S (DK) ANDERSEN, Peter DK-2700 Bronshoj (DK) OKKELS, Li, Mei, Meng DK-2880 Bagsvaerd (DK) WELDINGH, Karin DK-2200 Copenhagen N (DK) (74) Representative: Plougmann & Vingtoft A/S  Sundkrogsgade 9,P.O. Box 831 2100 Copenhagen 2100 Copenhagen (DK)