(19)

(11)

EP 1 278 884 A1

(12)

(43) Date of publication: 29.01.2003 Bulletin 2003/05 (21) Application number: 01937215.0 (22) Date of filing: 02.05.2001

(51) International Patent Classification (IPC)7: C12P 21/04 (86) International application number: PCT/US0114/349 (87) International publication number: WO 0108/3806 (08.11.2001 Gazette 2001/45)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 02.05.2000 US 563222 (71) Applicant: Epicyte Pharmaceutical, Inc. San Diego, CA 92121 (US)	(72) Inventors: HIATT, Andrew, C. San Diego, CA 92103 (US) HEIN, Mich, B. Fallbrook, CA 92028 (US) (74) Representative: Fiener, Josef  Patentanw. J. Fiener et col.P.O. Box 12 49 87712 Mindelheim 87712 Mindelheim (DE)