(19)
(11) EP 1 280 816 A1

(12)

(43) Date of publication:
05.02.2003 Bulletin 2003/06

(21) Application number: 01923945.8

(22) Date of filing: 16.04.2001
(51) International Patent Classification (IPC)7C07J 19/00, C07J 17/00, C07J 9/00, A61K 31/58, A61P 9/04, A61P 9/02, A61P 13/12, A61P 39/02, A61P 25/00, A61P 35/00
(86) International application number:
PCT/IL0100/347
(87) International publication number:
WO 0107/9256 (25.10.2001 Gazette 2001/43)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 17.04.2000 IL 13570700

(71) Applicant: YISSUM RESEARCH DEVELOPMENT COMPANYOF THE HEBREW UNIVERSITY OF JERUSALEM
91390 Jerusalem (IL)

(72) Inventors:
  • LICHTSTEIN, David
    Ramot97735 Jerusalem (IL)
  • DEUTSCH, Joseph
    96348 Jerusalem (IL)

(74) Representative: Guerre, Dominique et al
Cabinet Germain et Maureau,12, rue Boileau,BP 6153
69466 Lyon Cedex 06
69466 Lyon Cedex 06 (FR)

   


(54) 19-NORBUFALIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM