DENDRITIC CELL CO-STIMULATORY MOLECULES

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EP 1 280 900 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	09.03.2011 Bulletin 2011/10

(45)	Mention of the grant of the patent:
	22.07.2009 Bulletin 2009/30

(21)	Application number: 01928894.3

(22)	Date of filing: 27.04.2001

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International Patent Classification (IPC):

C12N 15/12^(2006.01)
C07K 14/705^(2006.01)
A61K 38/17^(2006.01)
A61K 39/395^(2006.01)

C12N 15/62^(2006.01)
C07K 16/28^(2006.01)
A61K 39/00^(2006.01)

(86)	International application number:
	PCT/US2001/013430

(87)	International publication number:
	WO 2001/083750 (08.11.2001 Gazette 2001/45)

(54)	DENDRITIC CELL CO-STIMULATORY MOLECULES DENDRITZELL-SPEZIFISCHE KOSTIMULIERENDE MOLEKÜLE NOUVELLES MOLECULES CO-STIMULANTES DE CELLULE DENDRITIQUE

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

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Priority:

28.04.2000 US 200580 P
13.10.2000 US 240169 P
28.02.2001 US 794210 P

(43)	Date of publication of application:
	05.02.2003 Bulletin 2003/06

(73)	Proprietor: JOHNS HOPKINS UNIVERSITY
	Baltimore, MD 21205-2109 (US)

(72)	Inventors:
	PARDOLL, Drew, M. Brookville, MD 20833 (US) TSUCHIYA, Haruo Baltimore, MD 21239 (US) GORSKI, Kevin, S. Woodbury,MN 55125 (US) TSENG, Su-Yi Baltimore, MD 21218 (US)

(74)	Representative: Wright, Simon Mark et al
	J.A. Kemp & Co. 14 South Square Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)

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References cited: :

EP-A- 1 074 617
WO-A-00/61612
WO-A-01/94413
WO-A-02/02587
WO-A-02/24891
WO-A-95/05464
US-A- 5 861 310

WO-A-00/55375
WO-A-01/34629
WO-A-02/00692
WO-A-02/08279
WO-A-92/00092
WO-A-97/24447

TSENG SU-YI ET AL: "B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells." JOURNAL OF EXPERIMENTAL MEDICINE, vol. 193, no. 7, 2 April 2001 (2001-04-02), pages 839-845, XP002189416 ISSN: 0022-1007
DATABASE EM_MUS [Online] EMBL; Accession NO: AF142780, 1 June 1999 (1999-06-01) TSENG S Y ET AL: "Mus musculus Butyrophilin-like protein (Btdc) mRNA, complete cds." XP002189417 cited in the application
DATABASE EM_HUM [Online] EMBL; Accession NO: AK001872, 22 February 2000 (2000-02-22) ISOGAI T ET AL: "Homo sapiens cDNA FLJ11010 fis" XP002189418
CHEN L ET AL: "COSTIMULATION OF ANTITUMOR IMMUNITY BY THE B7 COUNTERRECEPTOR OF THE T LYMPHOCYTE MOLECULES CD28 AND CTLA-4" CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 71, 24 December 1992 (1992-12-24), pages 1093-1102, XP000941406 ISSN: 0092-8674
GERSTMAYER BERNHARD ET AL: "Costimulation of T-cell proliferation by a chimeric B7-antibody fusion protein." CANCER IMMUNOLOGY IMMUNOTHERAPY, vol. 45, no. 3-4, November 1997 (1997-11), pages 156-158, XP002932422 ISSN: 0340-7004
HENRY J ET AL: "Structure and evolution of the extended B7 family" IMMUNOLOGY TODAY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, vol. 20, no. 6, June 1999 (1999-06), pages 285-288, XP004169718 ISSN: 0167-5699
YOSHINAGA S K ET AL: "T-cell co-stimulation through B7RP-1 and ICOS" NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 402, 16 December 1999 (1999-12-16), pages 827-832, XP002157212 ISSN: 0028-0836 cited in the application
TOWNSEND S E ET AL: "TUMOR REJECTION AFTER DIRECT COSTIMULATION OF CD8+T CELLS BY B7-TRANSFECTED MELANOMA CELLS" SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 259, 15 January 1993 (1993-01-15), pages 368-370, XP000943266 ISSN: 0036-8075 cited in the application

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).