(19)

(11)

EP 1 280 918 A2

(12)

(88) Date of publication A3: 19.09.2002 (43) Date of publication: 05.02.2003 Bulletin 2003/06 (21) Application number: 01935320.0 (22) Date of filing: 11.05.2001

(51) International Patent Classification (IPC)7: C12N 15/53, C12N 15/55, C12N 9/16, C12N 9/20, C12N 9/02, C12N 15/63, C12N 1/21, C12N 5/10, C12Q 1/26, C12N 1/34, C12Q 1/68, C07K 16/40, G01N 33/53, G01N 33/68, A61K 38/44, A61K 38/46, A61K 39/395 (86) International application number: PCT/US0115/210 (87) International publication number: WO 0108/5956 (15.11.2001 Gazette 2001/46)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 11.05.2000 US 203511 P 25.05.2000 US 207903 P 07.06.2000 US 210150 P 23.06.2000 US 213392 P (71) Applicant: Incyte Genomics, Inc. Palo Alto, CA 94304 (US)

(72) Inventors: DAS, Debopriya Mountain View, CA 94040 (US) REDDY, Roopa Sunnyvale, CA 94086 (US) YAO, Monique, G. Mountain View, CA 94043 (US) NGUYEN, Danniel, B. San Jose, CA 95118 (US) LU, Yan Palo Alto, CA 94303 (US) TRIBOULEY, Catherine, M. San Francisco, CA 94107 (US) YUE, Henry Sunnyvale, CA 94087 (US) KHAN, Farrah, A. Mountain View, CA 94040 (US) GANDHI, Ameena, R. Menlo Park, CA 94025 (US) AU-YOUNG, Janice Brisbane, CA 94005 (US) LAL, Preeti Santa Clara, CA 95056 (US) KEARNEY, Liam San Francisco, CA 94127 (US) ELLIOTT, Vicki, S. San Jose, CA 95121 (US) DING, Li Palo Alto, CA 94306 (US) THORNTON, Michael Woodside, CA 94062-2612 (US) (74) Representative: Wright, Simon Mark  J.A. Kemp & Co.14 South SquareGray's Inn London WC1R 5JJ London WC1R 5JJ (GB)