(19)
(11) EP 1 282 440 A1

(12)

(43) Date of publication:
12.02.2003 Bulletin 2003/07

(21) Application number: 01929585.6

(22) Date of filing: 19.04.2001
(51) International Patent Classification (IPC)7A61K 39/395, A61K 31/5685, A61K 31/4196, A61P 35/00
// A61K39:395, A61K31:5685, A61K39:395, A61K31:4196
(86) International application number:
PCT/EP0104/468
(87) International publication number:
WO 0108/7334 (22.11.2001 Gazette 2001/47)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 15.05.2000 US 571355

(71) Applicants:
  • Pharmacia Italia S.p.A.
    20152 Milano (IT)
  • PHARMACIA & UPJOHN COMPANY
    Kalamazoo,Michigan 49001 (US)

(72) Inventors:
  • MASSIMINI, Giorgio
    I-20081 Abbiategrasso-(Milan) (IT)
  • PISCITELLI, Gabriella
    I-20136 Milan (IT)
  • PURANDARE, Dinesh
    Branchburg, NJ 08876 (US)

(74) Representative: Longoni, Alessandra et al
Pharmacia Italia S.p.A.,Patent DepartmentViale Pasteur 10
20014 Nerviano (Milano)
20014 Nerviano (Milano) (IT)

   


(54) AROMATASE INHIBITORS AND MONOCLONAL ANTI-HER2 ANTIBODIES AS ANTITUMOR AGENTS