(19)

(11)

EP 1 284 719 A2

(12)

(88) Date of publication A3: 30.05.2002 (43) Date of publication: 26.02.2003 Bulletin 2003/09 (21) Application number: 01914134.0 (22) Date of filing: 28.03.2001

(51) International Patent Classification (IPC)7: A61K 31/00, A61K 31/4422, A61K 45/06, A61P 13/12 (86) International application number: PCT/IB0100/518 (87) International publication number: WO 0107/4390 (11.10.2001 Gazette 2001/41)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 04.04.2000 GB 0008332 (71) Applicants: Pfizer Limited Sandwich,Kent CT13 9NJ (GB) GB  PFIZER INC. New York, N.Y. 10017 (US) AT BE CH CY DE DK ES FI FR GR IE IT LU MC NL PT SE TR LI	(72) Inventor: FOSTER, Adrian PaulPfizer Global Res. & Dev SandwichKent CT13 9NJ (GB) (74) Representative: Atkinson, Jonathan David Mark  Urquhart-Dykes & LordTower HouseMerrion Way Leeds LS2 8PA Leeds LS2 8PA (GB)