(19)
(11) EP 1 285 090 A1

(12)

(43) Date of publication:
26.02.2003 Bulletin 2003/09

(21) Application number: 01932618.0

(22) Date of filing: 24.04.2001
(51) International Patent Classification (IPC)7C12Q 1/68, C12P 19/34
(86) International application number:
PCT/US0113/136
(87) International publication number:
WO 0108/1631 (01.11.2001 Gazette 2001/44)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 25.04.2000 US 558245

(71) Applicant: DNA Sciences, Inc.
Fremont, CA 94555-3613 (US)

(72) Inventors:
  • XU, Hua
    Sunnyvale, CA 94087 (US)
  • MATHIES, Richard, A.
    Moraga, CA 94556 (US)

(74) Representative: Raynor, John et al
W.H. Beck, Greener & Co7 Stone BuildingsLincoln's Inn
London WC2A 3SZ
London WC2A 3SZ (GB)

   


(54) DETECTION OF NUCLEOTIDE SEQUENCE VARIATIONS VIA THE PROOFREADING ACTIVITY OF POLYMERASES