(19)
(11) EP 1 286 980 A2

(12)

(88) Date of publication A3:
16.01.2003

(43) Date of publication:
05.03.2003 Bulletin 2003/10

(21) Application number: 01918212.0

(22) Date of filing: 12.03.2001
(51) International Patent Classification (IPC)7C07D 307/32, C07D 315/00
(86) International application number:
PCT/US0105/800
(87) International publication number:
WO 0107/2731 (04.10.2001 Gazette 2001/40)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 24.03.2000 US 192148 P

(71) Applicant: ELI LILLY AND COMPANY
Indianapolis, Indiana 46285 (US)

(72) Inventors:
  • ZHANG, Tony, Yantao
    Indianapolis, IN 46236 (US)
  • ZHANG, Hongbin,401 Qiang Wei Court
    650224 Kunming, Yunnan (CN)
  • PROCTOR, Christophor, Scott
    Indianapolis, IN 46214 (US)

(74) Representative: Burnside, Ivan John et al
Eli Lilly and Company LimitedLilly Research CentreErl Wood ManorSunninghill Road
Windlesham, Surrey GU20 6PH
Windlesham, Surrey GU20 6PH (GB)

   


(54) ENANTIOSELECTIVE PROCESS FOR PREPARING ARYLATED LACTONES AND DERIVATIVES