(19)
(11) EP 1 289 944 A2

(12)

(88) Date of publication A3:
14.03.2002

(43) Date of publication:
12.03.2003 Bulletin 2003/11

(21) Application number: 01920617.6

(22) Date of filing: 21.03.2001
(51) International Patent Classification (IPC)7: C07C 323/20, C07C 323/60, C07H 15/203, A61K 31/70, A61P 29/00, A61P 3/06
(86) International application number:
PCT/US0109/049
(87) International publication number:
WO 0107/0757 (27.09.2001 Gazette 2001/39)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 21.03.2000 US 191046 P

(71) Applicant: Atherogenics, Inc.
Alpharetta, GA 30004 (US)

(72) Inventors:
  • MENG, Charles, Q.
    Alpharetta, GA 30005 (US)
  • HOONG, Lee, K.
    Suwanee, GA 30024 (US)
  • SOMERS, Patricia, K.
    Fort Collins, CO 80525 (US)
  • SIKORSKI, James, A.
    Alpharetta, GA 30022 (US)

(74) Representative: Hallybone, Huw George et al
Carpmaels and Ransford,43 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)

   


(54) THIOKETALS AND THIOETHERS FOR INHIBITING THE EXPRESSION OF VCAM-1