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EP 1 290 196 A1

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(43) Date of publication: 12.03.2003 Bulletin 2003/11 (21) Application number: 00941479.8 (22) Date of filing: 16.06.2000

(51) International Patent Classification (IPC)7: C12N 15/62, C12N 15/63, C12N 15/67, C12N 15/86, C12N 7/01, C12N 5/10, C07K 14/47, C12Q 1/68, A01K 67/027, A61K 48/00 (86) International application number: PCT/US0016/621 (87) International publication number: WO 0109/8507 (27.12.2001 Gazette 2001/52)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (71) Applicant: ARIAD GENE THERAPEUTICS, INC. Cambridge, MA 02139-4234 (US)	(72) Inventors: NATESAN, Sridaran Chestnut Hill, MA 02167 (US) GILMAN, Michael, Z. Newton, MA 02168 (US) (74) Representative: VOSSIUS & PARTNER  Siebertstrasse 4 81675 München 81675 München (DE)