(19)

(11)

EP 1 292 363 A2

(12)

(88) Date of publication A3: 10.10.2002 (43) Date of publication: 19.03.2003 Bulletin 2003/12 (21) Application number: 01937250.7 (22) Date of filing: 08.05.2001

(51) International Patent Classification (IPC)7: A61P 3/06, A61K 31/255 // (A61K31/255, 31:19) (86) International application number: PCT/US0114/804 (87) International publication number: WO 0109/3845 (13.12.2001 Gazette 2001/50)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 07.06.2000 US 210056 P (71) Applicant: WARNER-LAMBERT COMPANY Morris Plains,New Jersey 07950 (US)	(72) Inventors: AUERBACH, Bruce Jeffrey Ann Arbor, MI 48105 (US) ZOBEL, Donna,Lee Ann Arbor, MI 48103 (US) (74) Representative: Tesch, Rudolf, Dr. et al Warner-Lambert Company,c/o Gödecke GmbH,Patents 79090 Freiburg 79090 Freiburg (DE)