(19)
(11) EP 1 292 588 A1

(12)

(43) Date of publication:
19.03.2003 Bulletin 2003/12

(21) Application number: 01944251.6

(22) Date of filing: 01.06.2001
(51) International Patent Classification (IPC)7: C07D 311/58
(86) International application number:
PCT/US0117/977
(87) International publication number:
WO 0109/4334 (13.12.2001 Gazette 2001/50)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 02.06.2000 US 208766 P

(71) Applicant: Eli Lilly & Company
Indianapolis,Indiana 46285 (US)

(72) Inventors:
  • ANTOINE, Luc
    B-3401 Landen (BE)
  • BOUQUEL, Pascal
    F-55600 Breux (FR)
  • BORGHESE, Alfio
    B-1470 Baisy-Thy (BE)
  • GORISSEN, Hugo
    B-1390 Grez-Doiceau (BE)
  • KHAU, Vien, V.
    Carmel, IN 46038 (US)
  • MARTINELLI, Michael
    Zionsville, IN 46077 (US)
  • MERSCHAERT, Alain
    B-7850 Petit-Enghien (BE)
  • RUHTER, Gerd
    21129 Hamburg (DE)
  • RYPENS, Carine
    F-91120 Palaiseau (FR)

(74) Representative: Mallalieu, Catherine Louise et al
D. Young & Co.,21 New Fetter Lane
London EC4A 1DA
London EC4A 1DA (GB)

   


(54) METHODS FOR RESOLVING CHIRAL (2S) AND (2R) CHROMANES