(19)

(11)

EP 1 294 396 A2

(12)

(88) Date of publication A3: 01.08.2002 (43) Date of publication: 26.03.2003 Bulletin 2003/13 (21) Application number: 01943659.1 (22) Date of filing: 29.06.2001

(51) International Patent Classification (IPC)7: A61K 39/00 (86) International application number: PCT/GB0102/877 (87) International publication number: WO 0200/2137 (10.01.2002 Gazette 2002/02)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 30.06.2000 GB 0015935 (71) Applicant: University of Sheffield Sheffield S10 2TN (GB)	(72) Inventor: MOORE, Harry,Univ. of Sheffield Sheffield S10 2TN (GB) (74) Representative: Harrison Goddard Foote  Belgrave HallBelgrave Street Leeds LS2 8DD Leeds LS2 8DD (GB)