(19)
(11) EP 1 294 949 A2

(12)

(88) Date of publication A3:
08.08.2002

(43) Date of publication:
26.03.2003 Bulletin 2003/13

(21) Application number: 01961605.1

(22) Date of filing: 14.06.2001
(51) International Patent Classification (IPC)7C12Q 1/68, A61K 38/00, C07H 21/02
(86) International application number:
PCT/US0119/026
(87) International publication number:
WO 0109/6528 (20.12.2001 Gazette 2001/51)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 15.06.2000 US 211537 P
23.10.2000 US 241952 P
13.12.2000 US 254875 P
16.03.2001 US 276248 P
23.03.2001 US 277978 P
25.05.2001 US 293499 P

(71) Applicant: HUMAN GENOME SCIENCES, INC.
Rockville, MD 20850-3338 (US)

(72) Inventors:
  • YU, Guo-Liang
    Berkeley, CA 94705 (US)
  • NI, Jian
    Germantown, MD 20874 (US)
  • GENTZ, Reinder, L.
    Rockville, MD 20850 (US)
  • DILLON, Patrick, J.
    Carlsbad, CA 92009 (US)
  • HILBERT, David
    Bethesda, MD 20817 (US)

(74) Representative: VOSSIUS & PARTNER 
Siebertstrasse 4
81675 München
81675 München (DE)

   


(54) HUMAN TUMOR NECROSIS FACTOR DELTA AND EPSILON