(19)
(11) EP 1 297 132 A1

(12)

(43) Date of publication:
02.04.2003 Bulletin 2003/14

(21) Application number: 01947451.9

(22) Date of filing: 06.07.2001
(51) International Patent Classification (IPC)7: C12N 15/12, C12N 5/10, C12N 1/21, C07K 14/47, A01K 67/027, G01N 33/50
(86) International application number:
PCT/EP0107/830
(87) International publication number:
WO 0200/2769 (10.01.2002 Gazette 2002/02)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 06.07.2000 EP 00202362

(71) Applicant: Vlaams Interuniversitair Instituut voor Biotechnologie vzw.
9052 Zwijnaarde (BE)

(72) Inventors:
  • CRUTS, Marc
    B-2018 Antwerpen (BE)
  • DE JONGHE, Chris
    B-2650 Edegem (BE)
  • KUMAR SINGH, Samir
    B-2650 Edegem (BE)
  • VAN BROECKHOVEN, Christine
    B-2650 Edegem (BE)

   


(54) A NOVEL APP MUTATION ASSOCIATED WITH AN UNUSUAL ALZHEIMER'S DISEASE PATHOLOGY