(19)
(11) EP 1 297 175 A2

(12)

(88) Date of publication A3:
18.04.2002

(43) Date of publication:
02.04.2003 Bulletin 2003/14

(21) Application number: 01950770.6

(22) Date of filing: 29.06.2001
(51) International Patent Classification (IPC)7C12Q 1/00, G01N 33/53, G01N 33/543, G01N 33/566, G01N 33/567, A61K 38/04, C07K 5/00
(86) International application number:
PCT/US0120/969
(87) International publication number:
WO 0200/2488 (10.01.2002 Gazette 2002/02)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

(30) Priority: 30.06.2000 US 609361

(71) Applicant: The Regents of the University of California
Oakland, CA 94607-5200 (US)

(72) Inventors:
  • GUY, Rodney, K.
    San Francisco, CA 94130 (US)
  • BAXTER, John, D.
    San Francisco, CA 94127 (US)
  • DARIMONT, Beatrice
    San Francisco, CA 94122 (US)
  • FENG, Weijun
    San Francisco, CA 94131 (US)
  • FLETTERICK, Robert, J.
    San Francisco, CA 94131 (US)
  • KUSHNER, Peter, J.
    San Francisco, CA 94122 (US)
  • WAGNER, Richard, L.
    San Francisco, CA 94117 (US)
  • WEST, Brian, L.
    San Francisco, CA 94110 (US)
  • YAMAMOTO, Keith, R.
    San Francisco, CA 94114 (US)
  • GEISTLINGER, Timothy, R.
    San Francisco, CA 94117 (US)
  • ARNOLD, James, R.
    San Francisco, CA 94122 (US)
  • KUNTZ, Irwin, D.
    San Francisco, CA 94904 (US)

(74) Representative: Chapman, Paul Gilmour et al
Cruikshank & Fairweather,19 Royal Exchange Square
Glasgow G1 3AE
Glasgow G1 3AE (GB)

   


(54) METHODS AND COMPOUNDS FOR MODULATING NUCLEAR RECEPTOR COACTIVATOR BINDING