(19)

(11)

EP 1 299 327 A2

(12)

(88) Date of publication A3: 16.05.2002 (43) Date of publication: 09.04.2003 Bulletin 2003/15 (21) Application number: 01939871.8 (22) Date of filing: 31.05.2001

(51) International Patent Classification (IPC)7: C07C 1/00 (86) International application number: PCT/US0117/935 (87) International publication number: WO 0109/2469 (06.12.2001 Gazette 2001/49)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 31.05.2000 US 208240 P 13.12.2000 US 255299 P (71) Applicant: PBL Biomedical Labroratories New Brunswick,NJ 08901 (US)	(72) Inventor: PESTKA, Sidney West Caldwell, NJ 07006 (US) (74) Representative: VOSSIUS & PARTNER  Siebertstrasse 4 81675 München 81675 München (DE)