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(11)

EP 1 301 595 A2

(12)

(88) Date of publication A3: 30.01.2003 (43) Date of publication: 16.04.2003 Bulletin 2003/16 (21) Application number: 01935748.2 (22) Date of filing: 22.05.2001

(51) International Patent Classification (IPC)7: C12N 15/12, C12N 15/10, C12Q 1/68, C07K 14/705, C07K 16/28, A01K 67/027, A61K 38/17, A61K 39/395, G01N 33/53, G01N 33/577 (86) International application number: PCT/US0116/833 (87) International publication number: WO 0109/0359 (29.11.2001 Gazette 2001/48)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 22.05.2000 US 206222 P 25.05.2000 US 207476 P 02.06.2000 US 208834 P 02.06.2000 US 208861 P 07.06.2000 US 209868 P (71) Applicant: Incyte Genomics, Inc. Palo Alto, CA 94304 (US)

(72) Inventors: ARVIZU, Chandra S. San Jose, CA 95125 (US) TRIBOULEY, Catherine, M. San Francisco, CA 94107 (US) YAO, Monique, G. Mountain View, CA 94043 (US) GRIFFIN, Jennifer, A. Fremont, CA 94555 (US) THORNTON, Michael Woodside, CA 94062-2612 (US) LU, Yan Palo Alto, CA 94303 (US) KALLICK, Deborah, A. Menlo Park, CA 94025 (US) GANDHI, Ameena, R. Menlo Park, CA 94025 (US) AU-YOUNG, Janice Brisbane, CA 94005 (US) (74) Representative: Wright, Simon Mark  J.A. Kemp & Co.14 South SquareGray's Inn London WC1R 5JJ London WC1R 5JJ (GB)