(19)

(11)

EP 1 301 598 A2

(12)

(88) Date of publication A3: 28.11.2002 (43) Date of publication: 16.04.2003 Bulletin 2003/16 (21) Application number: 01959033.0 (22) Date of filing: 18.07.2001

(51) International Patent Classification (IPC)7: C12N 15/12, C12N 15/52, C12N 5/10, C07K 14/47, C07K 16/18, C07K 16/40, C12Q 1/68, C12N 9/00, A61K 38/17, A61K 38/53, A61K 39/00, G01N 33/50, G01N 33/53 (86) International application number: PCT/US0122/805 (87) International publication number: WO 0200/8255 (31.01.2002 Gazette 2002/05)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 21.07.2000 US 220111 P 29.09.2000 US 236860 P (71) Applicant: Incyte Genomics, Inc. Palo Alto, CA 94304 (US)

(72) Inventors: BAUGHN, Mariah, R. San Leandro, CA 94577 (US) LAL, Preeti Santa Clara, CA 95056 (US) LU, Dyung, Aina, M. San Jose, CA 95123 (US) NGUYEN, Danniel, B. San Jose, CA 95118 (US) TRIBOULEY, Catherine, M. San Francisco, CA 94107 (US) YAO, Monique, G. Carmel, Indiana 46033 (US) YUE, Henry Sunnyvale, CA 94087 (US) (74) Representative: Wright, Simon Mark  J.A. Kemp & Co.14 South SquareGray's Inn London WC1R 5JJ London WC1R 5JJ (GB)