(19)
(11) EP 1 301 624 A2

(12)

(88) Date of publication A3:
06.02.2003

(43) Date of publication:
16.04.2003 Bulletin 2003/16

(21) Application number: 01927400.0

(22) Date of filing: 14.03.2001
(51) International Patent Classification (IPC)7: C12Q 1/68, G01N 33/574
(86) International application number:
PCT/US0140/288
(87) International publication number:
WO 0107/5179 (11.10.2001 Gazette 2001/41)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR

(30) Priority: 31.03.2000 US 539567

(71) Applicants:
  • LUDWIG INSTITUTE FOR CANCER RESEARCH
    New York,New York 10158 (US)
  • INSTITUT NATIONAL DE LA SANTE ET DE LARECHERCHE MEDICALE (INSERM)
    75654 Paris Cédex 13 (FR)
  • INSTITUT GUSTAVE ROUSSY
    F-94805 Villejuif Cédex (FR)

(72) Inventors:
  • ECHCHAKIR, Hamid
    F-94805 Villejuif (FR)
  • MAMI-CHOUAIB, Fathia
    F-94805 Villejuif (FR)
  • VERGNON, Isabelle
    F-94805 Villejuif (FR)
  • CHOUAIB, Salem
    F-94805 Villejuif (FR)
  • BAURAIN, Jean FrançoisUni. Catholique de Louvain
    B-1200 Brussels (BE)
  • COULIE, Pierre G.,Uni. Catholique de Louvain
    B-1200 Brussels (BE)
  • BOON-FALLEUR, Thierry
    B-1200 Brussels (BE)

(74) Representative: Harrison Goddard Foote 
31 St Saviourgate
York Y01 8NQ
York Y01 8NQ (GB)

   


(54) PREPROCALCITONIN AS TUMOR REJECTION ANTIGEN PRECURSOR AND USES THEREOF