(19)

(11)

EP 1 303 280 A1

(12)

(43) Date of publication: 23.04.2003 Bulletin 2003/17 (21) Application number: 01946582.2 (22) Date of filing: 20.06.2001

(51) International Patent Classification (IPC)7: A61K 31/52, A61K 31/53, A61K 31/42, A61K 31/415 (86) International application number: PCT/US0119/719 (87) International publication number: WO 0200/0221 (03.01.2002 Gazette 2002/01)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 23.06.2000 US 213388 P 20.03.2001 US 277427 P (71) Applicant: University of Utah Research Foundation Salt Lake City, UT 84108 (US)	(72) Inventor: LEVENTHAL, Audie G.,University of Utah Salt Lake (US) (74) Representative: Gowshall, Jonathan Vallance  FORRESTER & BOEHMERTPettenkoferstrasse 20-22 80336 München 80336 München (DE)