(19)
(11) EP 1 307 183 A2

(12)

(88) Date of publication A3:
23.01.2003

(43) Date of publication:
07.05.2003 Bulletin 2003/19

(21) Application number: 01954266.1

(22) Date of filing: 06.08.2001
(51) International Patent Classification (IPC)7A61K 31/00, A61K 31/505, A61K 31/5355, A61K 31/535, A61K 31/4985, A61K 31/495, A61K 31/53, A61K 38/28, A61K 45/06, A61P 3/04, A61P 3/06, A61P 3/08, A61P 3/10, A61P 9/12, A61P 9/10, A61P 7/04
(86) International application number:
PCT/IB0101/428
(87) International publication number:
WO 0201/3798 (21.02.2002 Gazette 2002/08)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 11.08.2000 US 224928 P
15.12.2000 GB 0030649
02.02.2001 US 266083 P
15.03.2001 GB 0106465
15.03.2001 GB 0106468
13.07.2001 GB 0117134

(71) Applicants:
  • Pfizer Limited
    Sandwich,Kent CT13 9NJ (GB)

    GB 
  • PFIZER INC.
    New York, N.Y. 10017 (US)

    AT BE CH CY DE DK ES FI FR GR IE IT LU MC NL PT SE TR 

(72) Inventors:
  • FRYBURG, David Albert
    Groton, CT 06340 (US)
  • GIBBS, Earl Michael
    Groton, CT 06340 (US)
  • KOPPIKER, Nandan Parmanand
    Groton, CT 06340 (GB)

(74) Representative: Motion, Keith Robert et al
Pfizer LimitedPatents DepartmentRamsgate Road
Sandwich,Kent CT13 9NJ
Sandwich,Kent CT13 9NJ (GB)

   


(54) TREATMENT OF THE INSULIN RESISTANCE SYNDROME WITH SELECTIVE CGMP PDE5 INHIBITORS