(19)
(11) EP 1 307 191 A2

(12)

(88) Date of publication A3:
27.12.2002

(43) Date of publication:
07.05.2003 Bulletin 2003/19

(21) Application number: 01959427.4

(22) Date of filing: 27.07.2001
(51) International Patent Classification (IPC)7: A61K 31/404, A61P 27/06
(86) International application number:
PCT/US0124/220
(87) International publication number:
WO 0200/9702 (07.02.2002 Gazette 2002/06)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 28.07.2000 ES 200001916
16.03.2001 US 276885 P

(71) Applicants:
  • Inspire Pharmaceuticals, Inc.
    Durham, NC 27703 (US)
  • University Complutense de Madrid
    28040 Madrid (ES)

(72) Inventors:
  • PINTOR, Jesus, J.
    28002 Madrid (ES)
  • PERAL, Maria, A.
    28002 Madrid (ES)
  • PETERSON, Ward, M.
    Durham, NC 27703 (US)
  • PLOURDE, Robert, Jr.
    Durham, NC 27703 (US)
  • BROWN, Edward, G.
    Durham, NC 27703 (US)
  • YERXA, Benjamin, R.
    Raleigh, NC 27607 (US)

(74) Representative: Schüssler, Andrea, Dr. 
Kanzlei Huber & SchüsslerTruderinger Strasse 246
81825 München
81825 München (DE)

   


(54) USE OF INDOLE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT FOR REDUCING INTRACULAR PRESSURE