(19)
(11) EP 1 307 568 A2

(12)

(88) Date of publication A3:
16.01.2003

(43) Date of publication:
07.05.2003 Bulletin 2003/19

(21) Application number: 01957300.5

(22) Date of filing: 27.07.2001
(51) International Patent Classification (IPC)7C12N 15/57, C12N 9/64, C07K 16/40, G01N 33/68, A61K 38/43, G06F 15/00, G06F 19/00, C12Q 1/37
(86) International application number:
PCT/US0123/734
(87) International publication number:
WO 0201/0406 (07.02.2002 Gazette 2002/06)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 28.07.2000 US 221838 P

(71) Applicant: IMMUNEX CORPORATION
SeattleWashington 98101 (US)

(72) Inventors:
  • DUBOSE, Robert, F.
    Bellevue, WA 98006 (US)
  • WILEY, Steven, R.
    Seattle, WA 98119 (US)
  • BLACK, Roy, A.
    Seattle, WA 98115 (US)

(74) Representative: Dörries, Hans Ulrich, Dr. 
Dörries, Frank-Molnia & Pohlman,Triftstrasse 13
80538 München
80538 München (DE)

   


(54) METALLOPROTEINASE-DISINTEGRIN POLYPEPTIDES AND METHODS OF MAKING AND USE THEREOF