(19)

(11)

EP 1 311 252 A2

(12)

(88) Date of publication A3: 13.03.2003 (43) Date of publication: 21.05.2003 Bulletin 2003/21 (21) Application number: 01954296.8 (22) Date of filing: 16.08.2001

(51) International Patent Classification (IPC)7: A61K 31/00 (86) International application number: PCT/IB0101/470 (87) International publication number: WO 0201/5893 (28.02.2002 Gazette 2002/09)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 21.08.2000 GB 0020588 (71) Applicants: Pfizer Limited Sandwich,Kent CT13 9NJ (GB) GB  PFIZER INC. New York, N.Y. 10017 (US) AT BE CH CY DE DK ES FI FR GR IE IT LU MC NL PT SE TR	(72) Inventors: DAVIES, Michael, John Sandwich,Kent CT13 9NJ (GB) HUGGINS, Jonathan, Paul Sandwich,Kent CT13 9NJ (GB) PARUMS, Dinah, Velta Cambridge CB3 8LY (GB) (74) Representative: Atkinson, Jonathan David Mark et al Urquhart-Dykes & LordTower HouseMerrion Way Leeds LS2 8PA Leeds LS2 8PA (GB)