(19)
(11) EP 1 311 278 A1

(12)

(43) Date of publication:
21.05.2003 Bulletin 2003/21

(21) Application number: 01961861.0

(22) Date of filing: 02.08.2001
(51) International Patent Classification (IPC)7A61K 38/00, A61K 39/00, A61K 38/04, A61K 31/7105, A61K 31/711, C12N 15/09, C12N 15/01, C12N 15/00
(86) International application number:
PCT/US0124/286
(87) International publication number:
WO 0201/1748 (14.02.2002 Gazette 2002/07)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 07.08.2000 US 223165 P

(71) Applicant: Sloan-Kettering InstituteFor Cancer Research
New York,New York 10021 (US)

(72) Inventors:
  • ENGELHORN, Manuel
    New York, NY 10021 (US)
  • HOUGHTON, Alan, N.
    New York, NY 10021 (US)

(74) Representative: Frei, Alexandra Sarah 
Frei PatentanwaltsbüroPostfach 768
8029 Zürich
8029 Zürich (CH)

   


(54) METHOD AND COMPOSITION FOR IMMUNIZATION USING MIXED POOLS OF MUTATED NUCLEIC ACIDS OR PEPTIDES