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(11)

EP 1 313 440 A1

(12)

(43) Date of publication: 28.05.2003 Bulletin 2003/22 (21) Application number: 01962055.8 (22) Date of filing: 09.08.2001

(51) International Patent Classification (IPC)7: A61K 7/16, A61K 7/22, A61K 38/00, A61K 38/16, C07K 17/00 (86) International application number: PCT/US0125/101 (87) International publication number: WO 0201/3775 (21.02.2002 Gazette 2002/08)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 16.08.2000 US 225879 P (71) Applicant: ACOLOGIX, Inc. Emeryville,California 94608 (US)	(72) Inventors: YONEDA, Toshiyuki San Antonio, TX 78230 (US) NOMIZU, Motoyoshi Hokkaido 060-0808 (JP) KUMAGAI, Yoshinari Austin, TX 78703 (US) (74) Representative: VOSSIUS & PARTNER  Siebertstrasse 4 81675 München 81675 München (DE)