(19)
(11) EP 1 315 837 A2

(12)

(88) Date of publication A3:
19.09.2002

(43) Date of publication:
04.06.2003 Bulletin 2003/23

(21) Application number: 01968309.3

(22) Date of filing: 31.08.2001
(51) International Patent Classification (IPC)7C12Q 1/68, C07K 14/705, A61K 31/415
(86) International application number:
PCT/US0127/066
(87) International publication number:
WO 0202/0841 (14.03.2002 Gazette 2002/11)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 06.09.2000 US 230378 P

(71) Applicant: GLAXO GROUP LIMITED
Greenford, Middlesex UB6 ONN (GB)

(72) Inventors:
  • DAVIS, Kourtney, J,GlaxoSmithKline
    Research Triangle Park, NC 27709 (US)
  • FLING, Mary, E,GlaxoSmithKline
    Research Triangle Park, NC 27709 (US)
  • HUGHES, Arlene, R,GlaxoSmithKline
    Research Triangle Park, NC 27709 (US)
  • MANASCO, Penelope, K,GlaxoSmithKline
    Research Triangle Park, NC 27709 (US)
  • STUBBINS, Michael, J,GlaxoSmithKline
    Harlow, Essex CM195AW (GB)

(74) Representative: Giddings, Peter John, Dr. 
GlaxoSmithKlineCorporate Intellectual Property (CN9.25.1)980 Great West Road
Brentford, Middlesex TW8 9GS
Brentford, Middlesex TW8 9GS (GB)

   


(54) 5-HYDROXYTRYPTAMINE RECEPTOR GENE POLYMORPHISMS AND RESPONSE TO TREATMENT