(19)
(11) EP 1 318 839 A2

(12)

(88) Date of publication A3:
20.03.2003

(43) Date of publication:
18.06.2003 Bulletin 2003/25

(21) Application number: 01916717.0

(22) Date of filing: 21.03.2001
(51) International Patent Classification (IPC)7: A61K 48/00, C12N 15/861, A61P 35/00
(86) International application number:
PCT/US0109/042
(87) International publication number:
WO 0107/2341 (04.10.2001 Gazette 2001/40)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 24.03.2000 US 192015 P

(71) Applicant: CELL GENESYS, INC.
Foster City, CA 94404 (US)

(72) Inventors:
  • YU, De-Chao
    Foster City, CA 94404 (US)
  • CHEN, Yu
    Cupertino, CA 95014 (US)
  • HENDERSON, Daniel, R.
    Palo Alto, CA 94306 (US)

(74) Representative: Campbell, Patrick John Henry 
J.A. Kemp & Co.,14 South Square,Gray's Inn
London WC1R 5JJ
London WC1R 5JJ (GB)

   


(54) METHODS OF TREATING NEOPLASIA WITH COMBINATIONS OF TARGET CELL-SPECIFIC ADENOVIRUS, CHEMOTHERAPY AND RADIATION