(19)

(11)

EP 1 320 324 A2

(12)

(88) Date of publication A3: 27.06.2002 (43) Date of publication: 25.06.2003 Bulletin 2003/26 (21) Application number: 01975777.2 (22) Date of filing: 24.09.2001

(51) International Patent Classification (IPC)7: A61B 5/107, G01N 19/02 (86) International application number: PCT/US0142/265 (87) International publication number: WO 0202/4071 (28.03.2002 Gazette 2002/12)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 25.09.2000 GB 0023472 (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati,Ohio 45202 (US)

(72) Inventors: WOOLSTON, Robert Warwick CV15 9DG (GB) DAY, Shane, Alistair Warwick CV34 5TS (GB) QUAN, Ke, Ming West Chester, OH 45069 (US) STEPHENS, Tracy Warfield, Berkshire RG42 3DQ (GB) JACOBS, Linda Helen Thatcham,Berkshire RG18 9PQ (GB) (74) Representative: Kohol, Sonia et al Patent Department,Procter & Gamble Technical Centers Limited,Rusham Park,Whitehall Lane Egham,Surrey TW20 9NW Egham,Surrey TW20 9NW (GB)