ATBECHDEDKESFRGBGRITLILUNLSEMCPTIE......FI....CY..TR................................................*JDIM360 Ver 2.15 (14 Jul 2008) - 2999001/01320379CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120100602W173deBibliographieenBibliographyfrBibliographieEP01965468.0200109132003041720040719enenen002320320000921GB2010060220102220030625200326201004282010172009110620100602201022A61K 39/015 20060101AFI20020622BHEP A61K 39/00 20060101ALI20020622BHEP A61K 39/04 20060101ALI20020622BHEP A61P 31/06 20060101ALI20020622BHEP A61P 31/04 20060101ALI20020622BHEP A61P 31/12 20060101ALI20020622BHEP A61P 33/06 20060101ALI20020622BHEP deVERWENDUNG EINES REPLIKATIONDEFIZIENTEN POCKENVIRUSVEKTORS ZUR ERHÖHUNG DER CD4+ T-ZELL-IMMUNANTWORT GEGEN ANTIGENenUSE OF REPLICATION-DEFICIENT POXVIRUS VECTOR TO BOOST CD4+ T CELL IMMUNE RESPONSE TO ANTIGENfrUTILISATION D'UN VECTEUR DE POXVIRUS DEFICIENT POUR LA REPLICATION POUR STIMULERLA REPONSE IMMUNITAIRE DES LYMPHOCYTES T CD4+ CONTRE L'ANTIGENEWO-A-98/56919RAMSHAW I A ET AL: "The prime-boost strategy: exciting prospects for improved vaccination" IMMUNOLOGY TODAY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, vol. 21, no. 4, April 2000 (2000-04), pages 163-165, XP004194963 ISSN: 0167-5699PLEBANSKI MAGDALENA ET AL: "Protection from Plasmodium berghei infection by priming and boosting T cells to a single class I-restricted epitope with recombinant carriers suitable for human use." EUROPEAN JOURNAL OF IMMUNOLOGY, vol. 28, no. 12, December 1998 (1998-12), pages 4345-4355, XP002192944 ISSN: 0014-2980JOHNSON R P ET AL: "INDUCTION OF A MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I-RESTRICED CYTOTOXIC T-LYMPHOCYTE RESPONSE TO A HIGHLY CONSERVED REGION OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) GP120 IN SERONEGATIVE HUMANS IMMUNIZED WITH A CANDIDATE HIV-1 VACCINE" JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 68, no. 5, May 1994 (1994-05), pages 3145-3153, XP001027055 ISSN: 0022-538XSCHNEIDER J ET AL: "ENHANCED IMMUNOGENICITY FOR CD8+ T CELL INDUCTION AND COMPLETE PROTECTIVE EFFICACY OF MALARIA DNA VACCINATION BY BOOSTING WITH MODIEFIED VACCINIA VIRUS ANKARA" NATURE MEDICINE, NATURE PUBLISHING, CO, US, vol. 4, no. 4, April 1998 (1998-04), pages 397-402, XP000739989 ISSN: 1078-8956DENIS O ET AL: "Vaccination with plasmid DNA encoding Mycobacterial Antigen 85A stimulates a CD4+ and CD8+ T-cell epitopic repertoire broader than that stimulated by Mycobacterium tuberculosis H37Rv infection" INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY. WASHINGTON, US, vol. 66, no. 4, April 1998 (1998-04), pages 1527-1533, XP002173898 ISSN: 0019-9567MCSHANE HELEN ET AL: "Enhanced immunogenicity of CD4+ T-cell responses and protective efficacy of a DNA-modified vaccinia virus Ankara prime-boost vaccination regimen for murine tuberculosis." INFECTION AND IMMUNITY, vol. 69, no. 2, February 2001 (2001-02), pages 681-686, XP002192945 ISSN: 0019-9567A. LALVANI ET AL.: "Human cytolytic and interferon gamma-secreting CD8+ T lymphocytes specific for Mycobacterium tuberculosis" PNAS USA, vol. 95, 1998, pages 270-275,A. LALVANI & A.V.S. HILL: "Cytotoxic T-lymphocytes against malaria and tuberculosis: from natural immunity to vaccine design" vol. 95, 1998, pages 531-538,S.M. SMITH ET AL.: "Characterization of human Mycobacterium bovis bacille Calmette-Guerin-reactive CD8+ T cells" vol. 67, no. 10, 1999, pages 5223-5230,A.A. PATHAN ET AL.: "High frequencies of circulating IFN-gamma-secreting CD8 cytotoxic T cells specific for a novel MHC class I-restricted Mycobacterium tuberculosis epitope in M. tuberculosis-infected subjects without disease" EUROPEAN JOURNAL OF IMMUNOLOGY, vol. 30, no. 9, September 2000 (2000-09), pages 2713-2721,HILL, Adrian, V. S.Laurel Farm, Old HeadingtonOxford OX3 9DLGBMcSHANE, Helen397 Banbury RoadOxford OX2 7RFGBGILBERT, Sarah7 Manor Farm RdHorspath, Oxford O X33 1SDGBREECE, William67 Crescent RoadOxford OX4 2NYGBSCHNEIDER, Joerg11 Malford Rd, BartonOxford OX3 8BTGBOxford Biomedica (UK) Ltd07260930Medawar CenterRobert Robinson Avenue Oxford Science Park Oxford, OX4 4GAGBGoodfellow, Hugh Robin00093441Carpmaels & Ransford 43-45 Bloomsbury SquareLondon WC1A 2RAGBATBECHCYDEDKESFIFRGBGRIEITLILUMCNLPTSETRGB200100411620010913enWO200202422420020328200212