(19)

(11)

EP 1 322 633 A2

(12)

(88) Date of publication A3: 17.04.2003 (43) Date of publication: 02.07.2003 Bulletin 2003/27 (21) Application number: 01945195.4 (22) Date of filing: 25.05.2001

(51) International Patent Classification (IPC)7: C07D 333/32 (86) International application number: PCT/EP0106/015 (87) International publication number: WO 0109/2251 (06.12.2001 Gazette 2001/49)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 31.05.2000 US 208189 P (71) Applicant: Aventis Pharma Deutschland GmbH 65929 Frankfurt am Main (DE)	(72) Inventor: KAPINSKY, Joseph, M. Douglassville, PA 19518 (US)