(19)
(11) EP 1 323 422 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
08.03.2006 Bulletin 2006/10

(45) Mention of the grant of the patent:
26.10.2005 Bulletin 2005/43

(21) Application number: 02258924.6

(22) Date of filing: 20.12.2002
(51) International Patent Classification (IPC): 
A61K 31/5517(2000.01)
A61P 25/08(2000.01)
 A61K 9/08(1974.07)
A61P 23/00(2000.01)

(54)

Pharmaceutical composition comprising midazolam for buccal administration

Pharmazeutische Formulierung enhaltend Midazolam zur buccalen Verabreichung

Composition pharmaceutique contenant du midazolam pour une administration buccale

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SI SK TR
Designated Extension States:
AL LT LV MK RO

(30) Priority: 24.12.2001 GB 0130964

(43) Date of publication of application:
02.07.2003 Bulletin 2003/27

(73) Proprietor: Special Products Limited
London EC4A 1RS (GB)

(72) Inventor:
  • March, Graham Alan
    West Byfleet, Surrey KT1H 6EH (GB)

(74) Representative: Smaggasgale, Gillian Helen 
W.P. Thompson & Co, 55 Drury Lane
London WC2B 5SQ
London WC2B 5SQ (GB)


(56) References cited: : 
WO-A-00/62764
WO-A-99/09989
 WO-A-01/30391
   
  • SCOTT R C ET AL: "Buccal midazolam and rectal diazepam for treatment of prolonged seizures in childhood and adolescence: a randomised trial" LANCET, XX, XX, vol. 353, no. 9153, 20 February 1999 (1999-02-20), pages 623-626, XP004266026 ISSN: 0140-6736
  • ROELOFSE J A ET AL: "INTRANASAL MIDAZOLAM SPRAY IN ADULTS - PHARMACOKINETICS AND CLINICAL USE" SOUTH AFRICAN JOURNAL OF ANAESTHESIOLOGY AND ANALGESIA, GLENBARR PUBLICATIONS, PARKLANDS, SA, June 2000 (2000-06), pages 16-19, XP001025564 ISSN: 1027-9148
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).