(19)
(11) EP 1 326 600 A2

(12)

(88) Date of publication A3:
26.09.2002

(43) Date of publication:
16.07.2003 Bulletin 2003/29

(21) Application number: 01979788.5

(22) Date of filing: 12.10.2001
(51) International Patent Classification (IPC)7: A61K 31/40, A61K 31/495, A61K 9/08
(86) International application number:
PCT/US0132/054
(87) International publication number:
WO 0203/0421 (18.04.2002 Gazette 2002/16)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 13.10.2000 US 240536 P

(71) Applicant: Curis, Inc.
Cambridge, MA 02138 (US)

(72) Inventors:
  • Baxter, Anthony, D.
    Hertfordshire SG10 6BN (GB)
  • Boyd, Edward, A.
    Oxfordshire OX11 7QH (GB)
  • GUICHERIT, Oivin, M.
    Belmont, MA 24778 (US)
  • Price, Stephen
    Buckinghamshire HP225 UJ (GB)
  • RUBIN, Lee, D.
    Wellesley, MA 02481 (US)

(74) Representative: VOSSIUS & PARTNER 
Siebertstrasse 4
81675 München
81675 München (DE)

   


(54) MEDIATORS OF HEDGEHOG SIGNALING PATHWAYS, COMPOSITIONS AND USES RELATED THERETO